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USP37 activates EPAS1. 2 / 2

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"Among these DUBs , USP37 induced the most significant increase in HIF2alpha levels ( Fig. 2D ) ."

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"As a result, USP37 promotes HIF2alpha protein stability in an enzymatically dependent manner, and depletion of USP37 leads to HIF2alpha down-regulation in ccRCC."

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IndraLab

Statements

USP37 activates EPAS1. 2 / 2

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