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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

OASL inhibits USP18. 1 / 1

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"Other factors that can control properties of IFN signaling and impact outcome include various negative regulatory proteins like RNF125 that can influence the ubiquitination of PRRs [XREF_BIBR], OASL that physically inhibits RIG-I [XREF_BIBR, XREF_BIBR], USP18 that displaces JAK2 from the type one IFN receptor [XREF_BIBR], and multiple other proteins that dynamically regulate IFN signaling [XREF_BIBR]."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...