IndraLab

Statements

USP8 inhibits SMO. 3 / 10

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"USP8 Prevents the Localization of Smo to the Early Endosome."

22253573

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"The stimulation of Hh promotes Smo deubiquitination by ubiquitin specific protease 8 (USP8), which blocks Smo endocytosis and enhances Smo cell surface accumulation XREF_BIBR XREF_BIBR."

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"Moreover, we found that USP8 prevents Smo localization to early endosomes that are labeled with Rab5."

22253573

INDRA sources:

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IndraLab

Statements

USP8 inhibits SMO. 3 / 10

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