IndraLab

Statements

OTUD1 increases the amount of BST2. 5 / 5
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"OTUD1 Significantly Enhances BST-2 Surface Expression."
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"Given the substantial increase in BST-2 surface expression induced by OTUD1, their potential interaction was investigated."
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"Collectively, these findings suggest that K21 is a critical site for the regulatory effects of OTUD1 on BST-2 ubiquitination, and that OTUD1 may promote BST-2 expression by specifically catalyzing the removal of K48- and K63-linked ubiquitin chains from K21 of BST-2."
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"OTUD1 Enhances BST-2 Protein Levels Through Direct Interaction."
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"Consistent with the screening results, overexpression of OTUD1 in HeLa cells led to an elevation in the total cellular levels of BST-2 (Figure 2C)."
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