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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

Doxycycline inhibits USP13. 2 / 2

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"In vivo bioluminescent analysis confirmed that induced disruption of USP13 by doxycycline treatment significantly inhibited GSC tumor growth in mouse intracranial xenografts (XREF_FIG)."

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"To further confirm the clinical relevance of targeting USP13 in established GBM tumors, we applied the Tet-on inducible knockdown system to examine whether inducible disruption of USP13 by doxycycline affects the growth of established xenograft tumors and animal survival."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...