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P5091 activates HDM2/p53/p21. 1 / 1

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"For example, P5091, a small-molecule inhibitor of USP7, activates HDM2/p53/p21 signaling axis and exerts cytotoxicity in several multiple myeloma (MM) cell models, supporting future clinical investigations of USP7 inhibitors for the treatment of malignant hematological diseases 21."

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P5091 activates HDM2/p53/p21. 1 / 1

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