IndraLab

Statements


DRG DNMT3a decreases the amount of KCNA2. 2 / 2
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reach
"Blocking the SNL-induced increase in DRG DNMT3a via its genetic knockout or knockdown restored the expression of Kcna2, but not Kcna1 and Kcna4, in the injured DRG, whereas mimicking the SNL-induced increase in DRG DNMT3a via its genetic overexpression decreased the expression of Kcna2, but not Kcna4, in the DRG of naive rat."

reach
"These increases are DNMT3a-dependent as blocking the SNL-induced upregulation in DRG DNMT3a abolished the SNL-induced elevation in Kcna2 DNA methylation level at these two CpG sites."