IndraLab

Statements

Mutated CYLD inhibits NFkappaB. 2 / 2
| 2
reach
"Furthermore, nuclear translocation of Bcl-3, a component of reported NPC associated activated NF-kappaB signal p50/p50/Bcl -3, was inhibited upon CYLD WT expression, but not by CYLD mutants (XREF_SUPPLEMENTARY)."
28098136
reach
"Surprisingly, a non cleavable CYLD mutant does not impair TCR dependent canonical NF-kappaB activation, but does block activation of JNK, a critical step in TCR induced stimulation of multiple transcription factors and production of IL-2."
21868762