IndraLab

Statements

USP39 activates CTNNB1. 3 / 4
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reach
"Double knockdown of TRIM26 and USP39 eliminated the reduction of β-catenin caused by USP39 silencing."
36707504
reach
"Here, we prove that USP39 promotes HCC cell proliferation and migration by directly deubiquitin beta-catenin, a key molecular of Wnt/beta-catenin signaling pathway whose abnormal expression or activation results in several tumors, following its co-localization with USP39."
36707504
reach
"In detail, on one hand, USP39 decreases β-catenin degradation through its deubiquitination function to promote HCC progression."
36707504