IndraLab

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Pioglitazone inhibits RELA. 4 / 5
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"Herein, we report that oral administration of the pioglitazone reduced the NF-kappaB p65 activity in the lumbar spinal cord."
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"Treatment with pioglitazone decreased nuclear p65, attenuating AGS-induced HIV replication and IL-1β activation in AMs."
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"These results indicated that pioglitazone attenuates p65 migration through a reduction in p65 acetylation, resulting in the suppression of NF-κB activity.In the present study, we further explored the [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Wan et al. have shown that the PPAR gamma activator pioglitazone could attenuate caerulein induced p50 and p65 NF and kappaB dimer activity in the nucleus of caerulein treated AR42J cells [84]."
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