IndraLab

Statements


GRN inhibits TNFRSF1A. 3 / 6
1 | 2

"Collectively, these findings demonstrate that pgrn is a ligand of tnfr, an antagonist of tnf signaling, and plays a critical role in the pathogenesis of inflammatory arthritis in mice."

reach
"This interaction increases the expression of GRN in MCs, which can competitively inhibit the binding of TNFα and TNFR1 and provide anti-apoptotic advantages in BC."

reach
"PGRN prevents Ti-induced inflammatory osteolysis by at least partial inhibition of the binding of TNFα to TNFR1."