IndraLab

Statements

P14_3_3 binds KCNH2. 6 / 7
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"Kagan et al. found that 14-3-3 binds to HERG, increases I Kr , and shortens repolarization duration ( Kagan and McDonald, 2005 ; Kagan et al., 2002 )."
32173522
reach
"Kagan et al. found that 14-3-3 binds to HERG, increases I Kr , and shortens repolarization duration ( Kagan and McDonald, 2005 ; Kagan et al., 2002 )."
32173522
sparser
"A second level of β-AR/PKA regulation of HERG may occur with the association of adaptor proteins such as 14-3-3, which binds to HERG when the channel is phosphorylated and affects channel gating and duration of the response [ xref , xref ]."
22613764
sparser
"Kagan et al. [138] demonstrated an interaction between 14-3-3 and the human ether-a-go-go related gene (HERG) K + channel pore-forming subunit, leading to enhanced rectifier potassium current at more [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
15350836
sparser
"Thus, 14-3-3 interactions with HERG may provide a unique mechanism for plasticity in the control of membrane excitability and cardiac rhythm."
11953308
sparser
"Thus, 14-3-3 interactions with hERG provide a unique mechanism for plasticity in the autonomic control of stress-dependent regulation of cardiac membrane excitability."
16050263