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USP1 binds WDR48 and K48. 2 / 2

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"Hence, a deubiquitinase complex, USP1 and UAF1 complex, eliminates the K48-connected poly-ubiquitination of TBK1, blocks TBK1 protein degradation, and increases anti-viral responses [73] ."

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"Collectively, these data indicate that the USP1 and UAF1 complex selectively removes K48 linked ubiquitination of TBK1."

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IndraLab

Statements

USP1 binds WDR48 and K48. 2 / 2

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