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Small interfering RNA inhibits KCNH2. 2 / 2

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"Pharmacological K v 11.1 blockade (dofetilide) in rats had similar effect, and small interfering RNA inhibition of hERG in β and L cells increased insulin and GLP-1 secretion up to 50%."

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"To our knowledge, the kinetics of hERG inhibition by a specific KCNH2 siRNA has not been evaluated previously in the in vitro hERG assay."

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IndraLab

Statements

Small interfering RNA inhibits KCNH2. 2 / 2

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