IndraLab

Statements



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"Downregulation of USP22 reduces in vitro cancer cell proliferation, survival, migration, and invasion, and decreases in vivo tumor growth and metastasis [6, 10–13]."

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"The assay results showed that USP22 downregulation significantly inhibited the proliferation (XREF_FIG) and invasion (XREF_FIG) of U2OS and MG-63 cells."

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"Ablation of USP22 expression remarkably attenuates melanoma migration, invasion, and epithelial-mesenchymal transition in vitro and suppresses melanoma metastasis in vivo."

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"We found that downregulation of USP22 could inhibit Sao-2 cell proliferation, migration, invasion, and induce apoptosis."

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"However, Ao et al (31) reported that USP22 promoted cell proliferation but inhibited cell invasion in SW480 colon cancer through the STAT3/MMP9 pathway (31)."

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"In summary, USP22 downregulation reduces cancer cell proliferation, migration, and invasion and reduces tumor growth and metastasis in vivo."

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"USP22 depletion could significantly inhibit the proliferation and invasion, and promote the apoptosis of ATC cells in vitro."

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"We also suggested that downregulation of USP22 inhibited OS cell proliferation and invasion in vitro."

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"Downregulation of USP22 inhibits migration and invasion of Sao-2 cells."

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"In conclusion, USP22 attenuated the invasion capacity of colon cancer cells by inhibiting the STAT3 and MMP9 signaling pathway."

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"Moreover, USP22 downregulation repressed cell proliferation, invasion and epithelial-mesenchymal transition (EMT) via inactivation of PI3K/Akt signaling pathway in osteosarcoma cells (28)."

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"In colon cancer, USP22 was reported to attenuate the invasion capacity of colon cancer cells by inhibiting the STAT3 and MMP9 signaling pathway."

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"Downregulation of USP22 inhibited OS cell proliferation, invasion, and epithelial-mesenchymal transition (EMT) in vitro."

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"USP22 downregulation inhibited OS cell proliferation, invasion, and epithelial-mesenchymal transition (EMT) in vitro."

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"Downregulation of USP22 inhibited OS cell proliferation, invasion, and EMT in vitro."

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"Downregulation of USP22 Inhibited OS Cell Proliferation and Invasion In Vitro."

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"The results of in vitro and in vivo studies confirmed USP22 depletion reduced the growth and invasion of ATC cells by regulating the expression and activation of a series of pro tumorigenesis molecules."