IndraLab

Statements

CD4 binds ITGAM. 4 / 4
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"We hypothesized that the impairment in CD4 + T cell stimulation associated with CD11b + cells could result from the induction of a suppressor mechanism in CD11b + cells, as suppressor macrophages that induce T cell anergy have previously been described in mice harboring patent schistosome infections xref , xref ."
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"Small T1 tumors could be compared with T2 tumors as they were the same size, and tests of equality of means showed only the CD4:CD11b ratio to be significantly different ( p < 0.021)."
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"Protection against SLE-mediated GN in Sle123 →ApoA-I tg mice was associated with reductions in kidney infiltrating CD4 + T cells ( xref ) as well as lower CD11b + monocytic and NIMPR14 + neutrophil infiltrates ( xref )."
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"As shown in xref B, absence of C5aR1 activation in response to allergen exposure in C5aR1 − cDCs or in response to in vitro blockade of C5aR1 (1), released the break on CD40 expression (2), resulting in efficient interaction of CD11b + cDCs with CD4 + T cells (3) as a prerequisite to drive strong CD4 + T cell proliferation (4)."
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