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USP4 activates TGFBR. 1 / 1

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"Both USP15 and USP4 stimulate TGF-beta signaling by deubiquitylating and stabilizing two key signaling molecules in this pathway, TGF-beta receptor I (TbetaRI) and R-SMADs, suggesting that these two closely related DUBs act in concert to modulate central signaling processes that are involved in oncogenesis and innate immunity."

24399297

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IndraLab

Statements

USP4 activates TGFBR. 1 / 1

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