IndraLab

Statements


USP6 activates CXCL9. 2 / 2
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"To further test this feedforward model, we sought to confirm whether CXCL9/CXCL10 were produced by the USP6/RD-ES cells, because NK cells are also capable of producing these chemokines (29, 34–36)."

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"Upon activation, NK cells secrete IFNγ, which feeds back on USP6-expressing Ewing sarcoma cells to synergistically induce CXCL9/CXCL10."