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2'-O-methyluridine inhibits TBK1. 1 / 1
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"(E) The expression levels of IFNβ and IFNλ1 mRNAs in SARS-487 CoV2 infected Calu-3 cells were at low levels at 24 h.p.i., and this induction was inhibited by the 488 pretreatment of 10 uM BX-795, which blocks the TBK1 kinase activity, prior to SARSThe induction of and response to Type I/III IFNs in SARS-CoV2 infected cells could not 492 restrict the viral replication."
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