IndraLab

Statements

Carbon monoxide inhibits RELA. 4 / 4
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"CO donors induce Nrf2 activation and Nrf2 siRNA suppresses CO-induced p65 glutathionylation and inhibition."
24512908
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"XREF_BIBR, XREF_BIBR Moreover, CO inhibits vascular inflammation by interfering with the IKK dependent signaling pathway or by stimulating S glutathiolation of the NF-kappaB p65 subunit."
29170479
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"The generated CO effectively suppresses the secretion of interleukin (IL)-1beta, IL-6, and tumor necrosis factor (TNF)-alpha by inhibiting cell proliferation; inducing the activation of heme oxygenase (HO-1), and downregulating the expression of p38 MAPK, NF-kB (p50 and p65) and TLR-2."
32554130
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"Additionally, we observed that CO reduced the activation of transcription nuclear factor-kappaB p65 in DSS treated colon tissues."
21598422