IndraLab

Statements


3 | 2

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"USP27x, acting as a tumor suppressor, could bind to Bim upon its anti-apoptotic ERK dependent phosphorylation and counteract the following proteasomal degradation via its deubiquitinase activity."

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"Furthermore, like βTrCP1/2, the binding of USP27x to BIM was dependent upon ERK1/2 activation."