IndraLab

Statements

BCL2L11 binds USP27X. 8 / 8
4 | 3 1
sparser
"Binding of USP27x to BIM was dependent on the 42-101 amino acid region on BIM, as mutation of these sites on BIM disrupted binding to USP27x. xref Interestingly, binding of USP27x and βTrCP to BIM is independent, as knockdown of βTrCP did not reduce the association of BIM with USP27x."
37584295
reach
"Binding of USP27x to BIM was dependent on the 42-101 amino acid region on BIM, as mutation of these sites on BIM disrupted binding to USP27x."
37584295
biogrid
No evidence text available
27013495
reach
"Furthermore, like βTrCP1/2, the binding of USP27x to BIM was dependent upon ERK1/2 activation."
28548464
reach
"USP27x, acting as a tumor suppressor, could bind to Bim upon its anti-apoptotic ERK dependent phosphorylation and counteract the following proteasomal degradation via its deubiquitinase activity."
28279784
biogrid
No evidence text available
27013495
biogrid
No evidence text available
35044632
biogrid
No evidence text available
27013495