IndraLab

Statements

USP37 activates cisplatin. 4 / 4
| 4
reach
"USP37 overexpression also increased the formation of spheroid and chemo-resistance to cisplatin-induced growth inhibition (Fig. 5b, d)."
30482232
reach
"Additionally, USP37 knockdown inhibited tumorigenicity and increased anticancer effect of cisplatin in vivo."
30482232
reach
"These results indicated that USP37 downregulation attenuates breast cancer progression and enhances sensitivity to cisplatin in vivo."
30482232
reach
"Finally, we demonstrated that high level of USP37 mediated cisplatin or IR resistance in breast cancer in a BLM-dependent manner and clarified the role of USP37 as a potential therapeutic target in breast cancer."
34606619