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OTUD5 deubiquitinates Interferon. 2 / 2

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"For example, TNFAIP3, CYLD, USP3, USP4, USP15, USP25, and OTUD5 deubiquitinate key components of the IFN production pathway, including RIG-I, TRAF2, TRAF3, TRAF6, RIP1, and TRIF (reviewed in [93,94])."

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"TRIAD3A dependent TRAF3 proteasomal destruction, like TRAF3 de-ubiquitination by DUBA, halts the activation of TBK1 and IKKepsilon and subsequent IFN production."

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OTUD5 deubiquitinates Interferon. 2 / 2

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