IndraLab

Statements

USP28 activates proteolysis. 2 / 2
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"Herein, we identified that USP28, a deubiquitinase aberrantly upregulated in patients with ADPKD, selectively removed K48-linked polyubiquitination and reversed protein degradation of signal transducer and activator of transcription 3 (STAT3)."
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"ATG7 promoted USP28 protein expression, which directly bound to and deubiquinated CD44s protein and inhibited CD44s protein degradation."
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