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STAMBPL1 leads to the ubiquitination of Sestrin2-GATOR2. 1 / 1

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"Interestingly, Wang et al. reported that gastric cancer and colorectal cancer downregulate an E3 ubiquitin ligase RING finger protein 167 (RNF167) and upregulate a deubiquitinase STAMBPL1 that can prevent the ubiquitination of Sestrin2, decrease Sestrin2-GATOR2 interaction and increase mTORC1 signaling [119]."

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IndraLab

Statements

STAMBPL1 leads to the ubiquitination of Sestrin2-GATOR2. 1 / 1

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