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Mitoxantrone inhibits NFKBIA. 1 / 1

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"Mitoxantrone activated NFkappaB and stimulated IkappaBalpha degradation in the promyelocytic leukemia cell line HL60 but not in the variant cells, HL60 and MX2 cells, which lack the beta isoform of topoisomerase II and express a truncated alpha isoform that results in an altered subcellular distribution."

10940316

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IndraLab

Statements

Mitoxantrone inhibits NFKBIA. 1 / 1

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