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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP10 inhibits Cell Survival. 2 / 2

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"Their results show that the depletion of USP10 in A549 increased cell survival and decreased apoptosis through destabilizing MSH2 [32]."

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"Biologically, silenced USP10 in lung cancer cells contributes to the elongated cell survival and depressed apoptosis, partially through deubiquitinating the mismatch repair protein MSH2 [XREF_BIBR], or negatively modulating EIF4G1 mediated functions [XREF_BIBR]."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...