IndraLab

Statements


| 2

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"ARF-BP1 is a p53-specific E3 ligase that binds to USP4."
| PMC

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"USP4, for example, interacts directly with end resection factors CtIP and MRN [172], USP21 deubiquitinates and stabilizes BRCA2 to promote RAD51 binding and successful HR [173], and USP10 deubiquitinates and stabilizes p53 to promote its nuclear localization and apoptosis in response to DSBs [174]."