IndraLab

Statements

OTUB1 activates MYC. 4 / 4
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"A recent study shows that OTUB1 contributes to breast tumourigenesis by stabilizing MYC."
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"Moreover, OTUB1 mediated MYC protein stability is also confirmed in OTUB1-knockout mice."
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"Han et al., [53] recently discovered that the deubiquitinase OTUB1 can inhibit Myc degradation through ubiquitination."
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"Therefore, OTUB1 promotes breast tumorigenesis in vivo and in vitro via blocking MYC protein degradation."
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