IndraLab

Statements



sparser
"Although voltage-dependent inactivation of the volume-regulated Cl is not likely to be physiological in nonexcitable cells (), it can be used as a comparative criterion for currents carried by Cl or a[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

sparser
"As discussed in the companion papers ( xref ; xref ), one contributor in the CFTR pore may be arginine 347 in TM6, since mutations that remove positive charge at this position drastically reduce selectivity between Cl − and I − ( xref ), abolish voltage–dependent inhibition of Cl − currents by the lyotropic anion SCN − ( xref ), and reduce channel block by cytoplasmic disulfonic stilbenes ( xref )."

sparser
"The biophysical characteristics of an outwardly rectifying, time- and positive voltage-dependent inactivating Cl − current that is sensitive to both NPPB and DIDS is consistent with either I ClC3 or I Cl swell ( xref ; xref ; xref ; xref )."

sparser
"Here we report that BAPTA, EDTA and HEDTA produce fast, reversible, voltage-dependent inhibition of swelling-activated Cl(-) current (I(Cl,swell)) in LNCaP prostate cancer epithelial cells that is unrelated to their Ca(2+) binding."