IndraLab

Statements


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"These results suggest that PERK is not involved in the Nrf2 activation by USP10 in dopamine-treated SH-SY5Y cells."

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"USP10 promotes activation of the NRF2/HO-1 pathway through SIRT6 and attenuates LPS-induced renal tubular epithelial cell injury."

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"USP10 activation has recently been shown to promote dopamine neuron survival by stimulating the antioxidant Nrf2 activity (54)."

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"Collectively, these results suggest that USP10 promotes activation of the NRF2/HO-1 pathway through SIRT6 and attenuates LPS-induced renal tubular epithelial cell injury."

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"Ubiquitin-specific peptidase 10 (Usp10) modulates the nuclear factor-E2-related factor 2 (Nrf2)/antioxidant response element signaling pathway to inhibit hepatic steatosis and inflammation in nonalcoh[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"Conclusions This study found that USP10 activates the NRF2 / ARE signaling through SIRT6 ."

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"Our study revealed that USP10 attenuated sepsis-induced oxidative stress in kidney tissues and activated the NRF2 / ARE signaling pathway ."

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"Finally, we discovered that USP10 promoted activation of the NRF2/HO-1 pathway through SIRT6 and attenuated LPS-induced renal tubular epithelial cell injury."

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"Notably, USP10 was found to inhibit tubular epithelial cell apoptosis and activate the NRF2/ARE pathway via Sirtuin 6 (Sirt6) (Gao et al. 2021)."

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"This study found that USP10 activates the NRF2/ARE signaling through SIRT6."