IndraLab

Statements


A-935142 inhibits KCNH2. 1 / 1
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reach
"A-935142 significantly reduced the time constants (tau) of hERG channel activation at two example voltages (-10 mV : tau = 100 +/-17 ms vs. 164 +/-24 ms, n = 6, P < 0.01; +30 mV : tau = 16.7 +/-1.8 ms vs. 18.9 +/-1.8 ms, n = 5, P < 0.05) and shifted the voltage-dependence for hERG activation in the hyperpolarizing direction by 9 mV."