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OTULIN deubiquitinates IKBKG. 1 / 1
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"Deubiquitination effects of swine <span class="match term0">OTULIN</span> were identified. The interaction between porcine <span class="match term0">OTULIN</span> and PRRSV Nsp11 is dependent on the OTU domain. PRRSV Nsp11 recruits <span class="match term0">OTULIN</span> through a nonenzymatic combination to promote removal of linear ubiquitination targeting <span class="match term1">NEMO</span>, resulting in a superimposed effect that inhibits the production of type I IFNs."