IndraLab

Statements


USP46 deubiquitinates Histone_H2B. 6 / 6
| 6

reach
"Usp12 and Usp46 deubiquitinate both H2A and H2B and Uaf-1 is required for this reaction [XREF_BIBR]."

reach
"Joo et al. demonstrated that USP46 and USP12 containing fractions from HeLa cells can deubiquitinate histones H2A and H2B to control cell fate and gastrulation during Xenopus development [XREF_BIBR]."

reach
"In other species, USP46 deubiquitinates deubiquitinate histones H2A and H2B associated to USP12 and WDR48 proteins, reinforcing its epigenetic function [40]."

reach
"USP12 and USP46 prefer nucleosomal substrates and deubiquitinate both histone H2A and H2B in vitro and in vivo."

reach
"Both USP12 and USP46 deubiquitinate histone H2A and H2B, affecting Xenopus development (Joo et al., 2011), and, unlike USP1, these smaller USPs can simultaneously bind WDR20 in addition to WDR48 (Joo [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

reach
"It has also been reported that USP12 and USP46 deubiquitinate histone H2A and H2B thereby playing a role in Xenopus development."