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AKT inhibits USP8. 1 / 2

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"In the present study the linkage between PTEN loss, Akt activation, and USP8 levels and activity appeared to be somewhat different, and in our work Akt activation decreased, rather than enhanced, USP8 function by increasing USP8 ubiquitination and decreasing steady-state USP8 levels (data not shown)."

20484045

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IndraLab

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AKT inhibits USP8. 1 / 2

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