IndraLab

Statements

USP53 activates cell differentiation. 7 / 7
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"We hypothesized that USP53 may positively regulate the osteogenic differentiation of hBMSCs in vitro and that local delivery of AAV2-USP53 to calvarial defects would thus enhance bone formation."
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"USP53 has been found to promote osteogenic differentiation [3]."
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"These results suggested that knockdown of USP53 decreased the osteogenic differentiation of hBMSCs."
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"Overexpression of USP53 promoted the osteogenic differentiation of hBMSCs in vitro."
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"Thus, USP53 positively regulated the osteogenic differentiation of hBMSCs."
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"USP53 enhances osteogenic function and differentiation in human BMSCs by stabilizing key proteins associated with osteogenic differentiation and regulating the BMP signaling pathway."
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"In addition, USP53 overexpression increased the level of active beta-catenin and enhanced the osteogenic differentiation of hBMSCs."
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