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SCN2A inhibits PrP Sc. 2 / 2
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"5–12 Likewise, enaminonitriles, such as 4 and its analogues 5 – 7 ( Fig. 2 ), have shown biological activity ( 4 , 18 μM; 5 , 35 μM; 6 , 19 μM; 7 , 16 μM) against scrapie-infected mouse neuroblastoma [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"Exposure of scrapie infected neuroblastoma (ScN2a) cells to weak bases inhibited the formation of nascent PrP Sc."