IndraLab

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USP8 inhibits NFE2L2. 2 / 2

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"USP8 prevents aberrant NF-kappaB and Nrf2 activation by counteracting ubiquitin signals from endosomes."

38180476

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reach

"USP8 depletion causes aberrant accumulation of K63-linked ubiquitin chains on endosomes, where TAB2/3 and p62 are recruited, and activates NF-kappaB and Nrf2."

38180476

INDRA sources:

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IndraLab

Statements

USP8 inhibits NFE2L2. 2 / 2

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