IndraLab

Statements

Amodiaquine inhibits ACHE. 5 / 5
1 | 3 1
reach
"This suggests that the inhibition of AChE by amodiaquine may involve binding of the protonated diethylamino and phenolic hydroxyl functions to the anionic and esteric sites of the enzyme respectively."
7256355
reach
"Screening result -- Amodiaquine reactivates inhibited AChE."
26350723
reach
"First, Katz and coworkers investigated the ability of the antimalarial drug amodiaquine and its analog ADOC to reactivate paraoxon-, sarin- and DFP inhibited human AChE and demonstrated reactivation by ADOC being superior compared to 2-PAM for all three OP."
32506210
sparser
"This suggests that the inhibition of AChE by amodiaquine may involve binding of the protonated diethylamino and phenolic hydroxyl functions to the anionic and esteric sites of the enzyme respectively."
7256355
ctd
No evidence text available
29614332