IndraLab

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UCHL3 binds FOS. 2 / 2
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"Using ChIP-qPCR, we confirmed that this increased UCH-L3 gene expression is caused by direct binding of c-Fos to the UCH-L3 promoter ( xref )."
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"Further, c-Fos binds to UCHL3 promoter region and boosts its translation expression in GCSCs cells, which in turn promotes UCHL3 and downstream gene expression, resulting in β-catenin stabilization to maintain GCSCs stem cell properties (Fig.  xref )."
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