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NAC inhibits FOS. 4 / 4
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"We next ascertained that the ROS scavenger NAC, the EGFR inhibitor AG, the MEK inhibitor PD and the ROCK inhibitor Y prevent c-fos induction by LA (XREF_FIG)."
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"As shown in xref , both 15(S)-HETE and 15(S)-HPETE upregulated the mRNA levels of c-FOS and c-JUN, which was inhibited by NAC."
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"NAC in combination with vanadate appeared to increase the efficacy of c-fos and c-jun inhibition, while decreasing toxicity."
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"Therefore, these data indicate that BA and the antioxidant NAC effectively inhibited H 2 O 2 -induced activation of PKC, ERK and c-Fos."
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