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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

CALM binds KCNQ1 and KCNQ2. 2 / 2

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"WT and mutant Kv7.1 C-termini and Kv7.2 C-terminus did interact with CaM as assayed by HIS3 induction in the GAL4 based yeast two-hybrid system ( Fig. 4 B) while the negative controls did not produc[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

17482572

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sparser

"Disrupted CaM interactions with Kv7.1 ( xref ; xref ), Kv7.2 ( xref ; xref , xref ), heteromeric Kv7.2/Kv7.3 ( xref ), or Kv7.4 ( xref ) have been shown to be tightly associated with severely impaired Kv7 surface expression, which illustrates the vital role of CaM in Kv7 assembly and trafficking."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...