IndraLab

Statements

USP7 activates DNA replication. 6 / 6
| 2 4
eidos
"USP7 has also recently been shown to promote DNA replication via acting as a DUB for the UBL SUMO96 ."
28959952
reach
"Cartel et al. (2021) demonstrated that USP7 inhibition significantly reduces cell proliferation in vitro and in vivo, blocks the progression of DNA replication, and increases cell death in Acute Myeloid Leukemia (AML) [38]."
37373211
reach
"USP7 targeting by LANA appears to inhibit DNA replication, a phenomenon mirroring the situation reported for the functionally equivalent EBNA1 latency protein of Epstein-Barr virus."
31666375
reach
"In this paper, we demonstrate that inhibition of deubiquitinylase USP7 significantly reduces cell proliferation in vitro and in vivo, blocks DNA replication progression and increases cell death in AML."
32447346
eidos
"Inhibition of USP7 hinders DNA replication by reducing fork velocity and firing of new origins [ 50 ] ."
31324531
reach
"USP7 has also recently been shown to promote DNA replication via acting as a DUB for the UBL SUMO ."
28959952