IndraLab

Statements

USP7 activates DNA replication. 6 / 6
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"In this paper, we demonstrate that inhibition of deubiquitinylase USP7 significantly reduces cell proliferation in vitro and in vivo, blocks DNA replication progression and increases cell death in AML."
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"USP7 has also recently been shown to promote DNA replication via acting as a DUB for the UBL SUMO96 ."
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"USP7 has also recently been shown to promote DNA replication via acting as a DUB for the UBL SUMO ."
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"USP7 has also recently been shown to promote DNA replication via acting as a DUB for the UBL SUMO 96 ."
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eidos
"Inhibition of USP7 hinders DNA replication by reducing fork velocity and firing of new origins [ 50 ] ."
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"USP7 targeting by LANA appears to inhibit DNA replication, a phenomenon mirroring the situation reported for the functionally equivalent EBNA1 latency protein of Epstein-Barr virus."
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