IndraLab

Statements

IL10 inhibits IFNGR1. 7 / 7
| 1 6
sparser
"Moreover, IL-10 may directly inhibit proliferation and production of IL-2, IFN-γ, IL-4, IL-5, and TNF-α by CD4 + T cells, thus it regulates both Th1 and Th2 immune responses ( xref )."
29312229
sparser
"Inhibition of both IL-12 and IFN-γ by IL-10 promotes development of Th2 type cytokine pattern."
27918954
sparser
"Traditionally, the cytokines IL-2 and IFN-γ are inhibited by IL-10 [ xref ]."
25391391
sparser
"Moreover, IL-10 negatively inhibited the pro-inflammatory cytokines IFN-γ, TNF-α, IL-12β, and IL-2 that play roles in adaptive immune response [ xref ]."
26752299
sparser
"IL-10 inhibits TNF-α, IL-1β, or IFN-γ induced surface ICAM-1 protein expression in astrocytes, but does not have any effect on mRNA steady-state levels, suggesting translational or post-translational [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
10430040
reach
"We further observed that treatments with either IL-6 or IL-10 were unable to reduce IFNGR1 nor IFNGR2 staining at concentrations that sufficed to induce STAT phosphorylation (Fig S2E and F)."
31585982
sparser
"To assess its function, rdIL-10 was produced in human embryonic kidney 293 cells and its bioactivity was demonstrated through IL-10-induced inhibition of proinflammatory cytokine mRNA expression IFN-γ, TNF-α, and IL-2 of Con A-stimulated PBMC."
23668955