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USP51 deubiquitinates TWIST1. 7 / 7
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"USP51 promotes non-small cell lung carcinoma cell stemness by deubiquitinating TWIST1."
37422632
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"We found that USP51 deubiquitinates TWIST1, which is significantly upregulated in the tissues of patients with NSCLC and is closely associated with poor prognosis."
37422632
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"Our results show that USP51 maintains the stemness of NSCLC cells by deubiquitinating TWIST1."
37422632
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"Mechanistically, USP51 interacted with and deubiquitinated TWIST1, leading to TWIST1 protein stabilization."
37422632
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"USP51 deubiquitinates TWIST1."
37422632
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"USP51 interacted with TWIST1, and the ectopic USP51 expression decreased the polyubiquitination of TWIST1 in HCC827 cells in the presence of MG132 (Sigma, M7449), a specific inhibitor of proteasome activity (Fig. 5A)."
37422632
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"Overall, this study shows that USP51 deubiquitinates TWIST1 to maintain NSCLC cells’ stemness."
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