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Modified mutated CYLD inhibits cell differentiation. 2 / 2

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"Overexpression of non SUMOylatable mutant CYLD in neuroblastoma cells reduced retinoic acid induced NF-kappaB activation and differentiation of cells, but instead promoted cell death."

24909169

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"By contrast, the expression of a mutant CYLD C/S that inhibits the endogenous CYLD deubiquitination function impairs keratinocyte differentiation."

21900959

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IndraLab

Statements

Modified mutated CYLD inhibits cell differentiation. 2 / 2

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