IndraLab

Statements

BAP1 inhibits BAP1. 4 / 6
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"In these haplo-insufficient cells (designated as HAP1 BAP1 KO), there was a complete loss of BAP1 compared with the parental HAP1 WT cells."
28122578
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"There were no chromosomal losses in either the Bap1 or Nf2 regions."
28577549
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"Overexpression of wild-type BAP1 reversed the sensitivity of BAP1 knockout cells to RITA, while overexpression of the mutant BAP1 (C91S) with inactivated ubiquitinase did not produce any rescue effect."
37313811
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"Tumors with both miR-31 and BAP1 overexpression exhibited significantly higher levels of BAP1 compared to tumors with miR-31 overexpression, suggesting that BAP1 overexpression could rescue the BAP1 suppression caused by miR-31."
26885612