IndraLab

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USP15 activates C6orf89. 2 / 2

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"Endogenous BRAP appears to be constitutively poly- or multiply monoubiquitylated in our system; however, depletion of USP15 promotes the appearance of additional high molecular weight ubiquitylated species of BRAP."

23105109

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"Our results lead to the prediction that USP15 knockdown may recapitulate the effect of BRAP knockdown by destabilizing and thereby reducing the pool of BRAP that is able to sequester key components of the MAPK module, such as KSR1."

23105109

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IndraLab

Statements

USP15 activates C6orf89. 2 / 2

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