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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP15 activates C6orf89. 2 / 2

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"Endogenous BRAP appears to be constitutively poly- or multiply monoubiquitylated in our system; however, depletion of USP15 promotes the appearance of additional high molecular weight ubiquitylated species of BRAP."

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"Our results lead to the prediction that USP15 knockdown may recapitulate the effect of BRAP knockdown by destabilizing and thereby reducing the pool of BRAP that is able to sequester key components of the MAPK module, such as KSR1."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...