IndraLab

Statements

USP39 activates homologous recombination. 4 / 4
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"Next, we monitored the effect of the ZF domain in USP39-mediated HR or NHEJ repair."
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"Herein, we showed that the iUSP domain is also critical for USP39-mediated HR repair."
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"Consistent with previous results, we observed that USP39 depletion reduced both HR and NHEJ repair (Figure 2F)."
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"Remarkably, our study implies that USP39 also promotes HR via mechanisms shared with its splicing function."
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