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Stomach Neoplasms increases the amount of USP47. 1 / 1
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"Specifically, it is unclear whether and how genetic variants in USP genes are associated with GC susceptibility, and the underlying biological mechanisms and clinical implications of such susceptible SNPs in GC development are yet to be elucidated.In the present study, we identified a GC-associated susceptibility locus, rs72856331 (G>A), located in the promoter region of USP47 and delineated the molecular mechanism by which the GC risk–associated allele G of rs72856331 modulates the expression of USP47."